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gptkbp:instanceOf
|
gptkb:protein
transcription factor
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
leukemia
|
|
gptkbp:binds
|
specific DNA sequences
|
|
gptkbp:biologicalProcess
|
sequence-specific DNA binding
transcriptional activator activity
|
|
gptkbp:domain
|
DNA-binding domain
transactivation domain
|
|
gptkbp:encodedBy
|
gptkb:MYB_gene
|
|
gptkbp:expressedIn
|
hematopoietic cells
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
cell cycle regulation
regulation of gene expression
hematopoiesis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
transcription factor Myb
|
|
gptkbp:inhibitedBy
|
gptkb:miR-150
|
|
gptkbp:interactsWith
|
gptkb:CBP/p300
gptkb:c-Maf
gptkb:CREB-binding_protein
gptkb:Cyclin_D1
|
|
gptkbp:orthologIn
|
gptkb:A-Myb
gptkb:B-Myb
gptkb:c-Myb
gptkb:v-Myb
|
|
gptkbp:phosphorylates
|
Serine 11
Threonine 572
|
|
gptkbp:regulates
|
gptkb:BCL2_gene
gptkb:CD34_gene
gptkb:CDKN1A_gene
gptkb:FOS_gene
gptkb:GATA3_gene
gptkb:MYC_gene
apoptosis
cell differentiation
cell proliferation
cellular senescence
immune response
stem cell maintenance
oncogene expression
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:target
|
phosphorylation
sumoylation
ubiquitination
post-translational modifications
acetylation
|
|
gptkbp:UniProtID
|
P10242
|
|
gptkbp:bfsParent
|
gptkb:MYB
|
|
gptkbp:bfsLayer
|
6
|