Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:platelet-derived_growth_factor_receptor_alpha
gptkb:PDGFR-alpha |
| gptkbp:cellSurfaceMarker |
yes
|
| gptkbp:encodedBy |
gptkb:PDGFRA_gene
|
| gptkbp:expressedIn |
fibroblasts
astrocytes mesenchymal cells |
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:gene |
gptkb:PDGFRA
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD140a
|
| gptkbp:ligand |
gptkb:platelet-derived_growth_factor_(PDGF)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4q12
|
| gptkbp:mutationAssociatedWith |
gptkb:glioblastoma
hypereosinophilic syndrome gastrointestinal stromal tumors |
| gptkbp:role |
cell differentiation
cell proliferation embryonic development tumorigenesis |
| gptkbp:target |
gptkb:imatinib
gptkb:crenolanib |
| gptkbp:bfsParent |
gptkb:PDGFRA
gptkb:PDGFRA_gene gptkb:PDGF_receptor_alpha |
| gptkbp:bfsLayer |
7
|