platelet-derived growth factor (PDGF)
GPTKB entity
Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
growth factor |
| gptkbp:abbreviation |
gptkb:PDGF
|
| gptkbp:associatedWith |
gptkb:cancer
atherosclerosis angiogenesis fibrosis |
| gptkbp:binds |
PDGF receptor
|
| gptkbp:category |
cytokine
mitogen |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:function |
wound healing
stimulates cell growth stimulates cell proliferation stimulates cell differentiation |
| gptkbp:gene |
gptkb:PDGFC
gptkb:PDGFD gptkb:PDGFA gptkb:PDGFB |
| https://www.w3.org/2000/01/rdf-schema#label |
platelet-derived growth factor (PDGF)
|
| gptkbp:involvedIn |
embryonic development
tissue repair blood vessel formation |
| gptkbp:location |
extracellular space
|
| gptkbp:producedBy |
macrophages
platelets endothelial cells smooth muscle cells |
| gptkbp:recipient |
gptkb:PDGF_receptor_alpha
gptkb:PDGF_receptor_beta |
| gptkbp:regulates |
mesenchymal cell migration
mesenchymal cell proliferation |
| gptkbp:structure |
dimer
|
| gptkbp:subunit |
A chain
B chain C chain D chain |
| gptkbp:bfsParent |
gptkb:PDGFR
|
| gptkbp:bfsLayer |
6
|