Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:TNFR1
gptkb:TNF_receptor_superfamily_member_1A gptkb:Tumor_necrosis_factor_receptor_1 |
| gptkbp:cellSurfaceMarker |
yes
|
| gptkbp:encodedBy |
gptkb:TNFRSF1A_gene
|
| gptkbp:expressedIn |
many cell types
|
| gptkbp:foundIn |
gptkb:human
|
| gptkbp:function |
involved in inflammation
mediates apoptosis receptor for tumor necrosis factor alpha (TNF-α) |
| https://www.w3.org/2000/01/rdf-schema#label |
CD120a
|
| gptkbp:interactsWith |
gptkb:FADD
gptkb:TRADD gptkb:TRAF2 gptkb:RIPK1 |
| gptkbp:ligand |
gptkb:TNF-α
|
| gptkbp:locatedOnChromosome |
gptkb:12p13.31
|
| gptkbp:memberOf |
gptkb:TNF_receptor_superfamily
|
| gptkbp:molecularWeight |
55 kDa
|
| gptkbp:OMIM |
191190
|
| gptkbp:significance |
mutations associated with TRAPS (TNF receptor-associated periodic syndrome)
|
| gptkbp:structure |
extracellular, transmembrane, and cytoplasmic domains
|
| gptkbp:UniProtID |
P19438
|
| gptkbp:bfsParent |
gptkb:tumor_necrosis_factor_receptor_superfamily
gptkb:TNFR1 gptkb:TNF_receptor_superfamily |
| gptkbp:bfsLayer |
7
|