CBP (CREB-binding protein)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:CREBBP gptkb:KAT3A
gptkbp:associatedWith	gptkb:Rubinstein-Taybi_syndrome
gptkbp:coactivatorFor	gptkb:CREB gptkb:NF-kB gptkb:p53 nuclear hormone receptors
gptkbp:domain	gptkb:ZZ_domain gptkb:HAT_domain gptkb:KIX_domain gptkb:TAZ_domain gptkb:bromodomain
gptkbp:encodedBy	CREBBP gene
gptkbp:Entrez_Gene_ID	1387
gptkbp:enzymeCommissionNumber	EC 2.3.1.48
gptkbp:firstDescribed	1993
gptkbp:function	histone acetyltransferase transcriptional coactivator
gptkbp:interactsWith	gptkb:CREB gptkb:STAT_proteins gptkb:NF-kB gptkb:p53 nuclear receptors
gptkbp:locale	gptkb:nucleus
gptkbp:locatedOnChromosome	16p13.3
gptkbp:molecularWeight	~265 kDa
gptkbp:mutationAssociatedWith	gptkb:intellectual_disability gptkb:cancer congenital heart defects
gptkbp:orthologIn	gptkb:EP300
gptkbp:postTranslationalModification	phosphorylation acetylation
gptkbp:regulates	gene expression transcription factors chromatin structure
gptkbp:role	apoptosis cell differentiation development DNA repair cell growth tumor suppression
gptkbp:species	gptkb:Homo_sapiens
gptkbp:structure	multi-domain protein
gptkbp:UniProtID	gptkb:Q92793
gptkbp:bfsParent	gptkb:CREB
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	CBP (CREB-binding protein)