Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
transcriptional activation
|
| gptkbp:example |
gptkb:CBP
gptkb:p300 gptkb:GCN5 gptkb:PCAF |
| gptkbp:foundIn |
histone acetyltransferase enzymes
|
| gptkbp:fullName |
Histone Acetyltransferase domain
|
| gptkbp:function |
histone acetyltransferase activity
catalyzes acetylation of histone proteins |
| https://www.w3.org/2000/01/rdf-schema#label |
HAT domain
|
| gptkbp:InterPro |
IPR000182
|
| gptkbp:mechanismOfAction |
transfers acetyl group to lysine residues on histones
|
| gptkbp:mutationAssociatedWith |
can lead to altered gene expression
|
| gptkbp:presentIn |
eukaryotes
some prokaryotes |
| gptkbp:proteinFamily |
PF02184
|
| gptkbp:role |
regulation of gene expression
chromatin remodeling |
| gptkbp:structure |
conserved core region for acetyl-CoA binding
|
| gptkbp:bfsParent |
gptkb:CREB-binding_protein
|
| gptkbp:bfsLayer |
7
|