bromodomain

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:firstDescribed 1992
gptkbp:foundIn chromatin-associated proteins
gptkbp:function regulation of gene expression
https://www.w3.org/2000/01/rdf-schema#label bromodomain
gptkbp:involves gptkb:cancer
neurological disorders
inflammation
gptkbp:nameOrigin Drosophila gene 'brahma'
gptkbp:presentIn histone acetyltransferases
BET family proteins
transcriptional coactivators
gptkbp:recognizedBy acetylated lysine residues
gptkbp:structure approximately 110 amino acids
gptkbp:target small molecule inhibitors
gptkbp:bfsParent gptkb:BRG1
gptkb:CREB-binding_protein
gptkb:SMARCA2
gptkb:TIF1-gamma_protein
gptkb:TRIM33
gptkb:TRIM24
gptkbp:bfsLayer 7