immunoglobulin A (IgA)

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:monoclonal_antibody
gptkbp:associatedWith selective IgA deficiency
gptkbp:component secretory immune system
gptkbp:deficiencyCauses increased susceptibility to infections
gptkbp:foundIn mucous membranes
breast milk
tears
saliva
respiratory tract
urogenital tract
intestinal secretions
gptkbp:function immune defense
neutralization of pathogens
prevents pathogen adherence
gptkbp:gene IGH@ (immunoglobulin heavy locus)
https://www.w3.org/2000/01/rdf-schema#label immunoglobulin A (IgA)
gptkbp:molecularWeight ~160 kDa (monomer)
~385 kDa (dimer)
gptkbp:presentIn humans
mammals
gptkbp:producedBy plasma cells
gptkbp:structure dimer
monomer
gptkbp:subclassOf IgA1
IgA2
gptkbp:symbol gptkb:IgA
gptkbp:bfsParent gptkb:B_cell
gptkbp:bfsLayer 7