Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
gptkbp:associatedWith |
selective IgA deficiency
|
gptkbp:component |
secretory immune system
|
gptkbp:deficiencyCauses |
increased susceptibility to infections
|
gptkbp:foundIn |
mucous membranes
breast milk tears saliva respiratory tract urogenital tract intestinal secretions |
gptkbp:function |
immune defense
neutralization of pathogens prevents pathogen adherence |
gptkbp:gene |
IGH@ (immunoglobulin heavy locus)
|
https://www.w3.org/2000/01/rdf-schema#label |
immunoglobulin A (IgA)
|
gptkbp:molecularWeight |
~160 kDa (monomer)
~385 kDa (dimer) |
gptkbp:presentIn |
humans
mammals |
gptkbp:producedBy |
plasma cells
|
gptkbp:structure |
dimer
monomer |
gptkbp:subclassOf |
IgA1
IgA2 |
gptkbp:symbol |
gptkb:IgA
|
gptkbp:bfsParent |
gptkb:B_cell
|
gptkbp:bfsLayer |
7
|