CD79b

URI: https://gptkb.org/entity/CD79b
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName gptkb:Ig-beta
B29
gptkbp:component gptkb:B-cell_receptor_complex
gptkbp:discoveredIn 1991
gptkbp:domain gptkb:ITAM_(immunoreceptor_tyrosine-based_activation_motif)
immunoglobulin-like domain
gptkbp:encodedBy gptkb:CD79B_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000105369
974
gptkbp:expressedIn gptkb:B_lymphocytes
gptkbp:formsComplexWith gptkb:CD79a
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function signal transduction in B cells
gptkbp:HGNC_ID gptkb:HGNC:1690
https://www.w3.org/2000/01/rdf-schema#label CD79b
gptkbp:involvedIn B-cell activation
antigen receptor signaling pathway
gptkbp:locatedOnChromosome gptkb:17q23
gptkbp:location gptkb:plasma_membrane
gptkbp:marking gptkb:B-cell_lymphomas
gptkbp:molecularWeight 36 kDa
gptkbp:mutationAssociatedWith gptkb:agammaglobulinemia
gptkbp:OMIM 147245
gptkbp:orthologIn gptkb:Mus_musculus
gptkbp:phosphorylates gptkb:Syk_kinase
gptkbp:target antibody-drug conjugates (e.g., polatuzumab vedotin)
gptkbp:UniProtID P40259
gptkbp:bfsParent gptkb:B_cells
gptkbp:bfsLayer 6