B cell receptor (BCR)

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:BCR
membrane immunoglobulin
gptkbp:associatedWith gptkb:CD19
gptkb:CD21
gptkb:CD81
gptkbp:binds immune response
gptkbp:cause B cell differentiation
memory B cell formation
plasma cell formation
gptkbp:composedOf Ig-alpha (CD79A)
Ig-beta (CD79B)
membrane-bound immunoglobulin
gptkbp:domain constant region
cytoplasmic tail
transmembrane region
variable region
gptkbp:encodedBy immunoglobulin genes
gptkbp:firstDescribed 1970s
gptkbp:foundIn gptkb:B_cells
gptkbp:function signal transduction
antigen recognition
https://www.w3.org/2000/01/rdf-schema#label B cell receptor (BCR)
gptkbp:importantFor gptkb:allergy
autoimmunity
vaccine response
gptkbp:involvedIn adaptive immune response
humoral immunity
gptkbp:launched B cell activation
antibody production
clonal expansion
gptkbp:location gptkb:plasma_membrane
gptkbp:phosphorylates Src-family kinases
gptkbp:subjectOf immunology research
gptkbp:triggeredBy intracellular signaling cascades
gptkbp:bfsParent gptkb:B_cell
gptkbp:bfsLayer 7