Statements (37)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:BCR
membrane immunoglobulin |
gptkbp:associatedWith |
gptkb:CD19
gptkb:CD21 gptkb:CD81 |
gptkbp:binds |
immune response
|
gptkbp:cause |
B cell differentiation
memory B cell formation plasma cell formation |
gptkbp:composedOf |
Ig-alpha (CD79A)
Ig-beta (CD79B) membrane-bound immunoglobulin |
gptkbp:domain |
constant region
cytoplasmic tail transmembrane region variable region |
gptkbp:encodedBy |
immunoglobulin genes
|
gptkbp:firstDescribed |
1970s
|
gptkbp:foundIn |
gptkb:B_cells
|
gptkbp:function |
signal transduction
antigen recognition |
https://www.w3.org/2000/01/rdf-schema#label |
B cell receptor (BCR)
|
gptkbp:importantFor |
gptkb:allergy
autoimmunity vaccine response |
gptkbp:involvedIn |
adaptive immune response
humoral immunity |
gptkbp:launched |
B cell activation
antibody production clonal expansion |
gptkbp:location |
gptkb:plasma_membrane
|
gptkbp:phosphorylates |
Src-family kinases
|
gptkbp:subjectOf |
immunology research
|
gptkbp:triggeredBy |
intracellular signaling cascades
|
gptkbp:bfsParent |
gptkb:B_cell
|
gptkbp:bfsLayer |
7
|