Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
| gptkbp:binds |
gptkb:Fc_receptors
antigens |
| gptkbp:canCross |
gptkb:placenta
|
| gptkbp:composedOf |
two heavy chains
two light chains |
| gptkbp:discoveredBy |
gptkb:Arne_Tiselius
|
| gptkbp:discoveredIn |
1950s
|
| gptkbp:encodedBy |
IGHG genes
|
| gptkbp:foundIn |
blood
extracellular fluid |
| gptkbp:function |
immune response
opsonization activation of complement system neutralization of pathogens |
| gptkbp:halfLife |
about 21 days
|
| https://www.w3.org/2000/01/rdf-schema#label |
immunoglobulin G (IgG)
|
| gptkbp:molecularWeight |
about 150 kDa
|
| gptkbp:mostAbundantAntibodyIn |
human serum
|
| gptkbp:percentageOfSerumAntibodies |
~75%
|
| gptkbp:presentIn |
all mammals
|
| gptkbp:producedBy |
plasma cells
|
| gptkbp:provides |
passive immunity to fetus
|
| gptkbp:structure |
Y-shaped
|
| gptkbp:subclassOf |
gptkb:IgG2
gptkb:IgG3 gptkb:IgG1 gptkb:IgG4 immune response |
| gptkbp:usedIn |
immunotherapy
diagnostic tests |
| gptkbp:bfsParent |
gptkb:B_cell
|
| gptkbp:bfsLayer |
7
|