|
gptkbp:instanceOf
|
gptkb:monoclonal_antibody
|
|
gptkbp:abbreviation
|
gptkb:IgE
|
|
gptkbp:binds
|
gptkb:basophils
gptkb:mast_cells
gptkb:FcεRI_receptor
|
|
gptkbp:category
|
gptkb:immune_response
|
|
gptkbp:component
|
immune system
|
|
gptkbp:discoveredBy
|
gptkb:Kimishige_Ishizaka
gptkb:Teruko_Ishizaka
|
|
gptkbp:discoveredIn
|
1966
|
|
gptkbp:elevatedIn
|
gptkb:atopic_dermatitis
asthma
parasitic infections
allergic diseases
|
|
gptkbp:encodedBy
|
gptkb:IGH_gene
|
|
gptkbp:foundIn
|
mammals
|
|
gptkbp:function
|
mediates allergic reactions
defense against parasitic infections
|
|
gptkbp:heavyChainType
|
epsilon
|
|
gptkbp:molecularWeight
|
~190 kDa
|
|
gptkbp:normalSerumConcentration
|
lowest among immunoglobulins
|
|
gptkbp:presentIn
|
blood
tissues
|
|
gptkbp:structure
|
gptkb:monomer
|
|
gptkbp:target
|
gptkb:omalizumab
anti-IgE therapy
|
|
gptkbp:triggeredBy
|
allergic inflammation
histamine release
|
|
gptkbp:usedIn
|
diagnosis of allergies
immunotherapy monitoring
|
|
gptkbp:bfsParent
|
gptkb:Xolair
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
immunoglobulin E (IgE)
|