Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
| gptkbp:abbreviation |
gptkb:IgE
|
| gptkbp:binds |
gptkb:basophils
gptkb:mast_cells gptkb:FcεRI_receptor |
| gptkbp:category |
immune response
|
| gptkbp:component |
immune system
|
| gptkbp:discoveredBy |
gptkb:Kimishige_Ishizaka
gptkb:Teruko_Ishizaka |
| gptkbp:discoveredIn |
1966
|
| gptkbp:elevatedIn |
gptkb:atopic_dermatitis
asthma parasitic infections allergic diseases |
| gptkbp:encodedBy |
gptkb:IGH_gene
|
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
mediates allergic reactions
defense against parasitic infections |
| gptkbp:heavyChainType |
epsilon
|
| https://www.w3.org/2000/01/rdf-schema#label |
immunoglobulin E (IgE)
|
| gptkbp:molecularWeight |
~190 kDa
|
| gptkbp:normalSerumConcentration |
lowest among immunoglobulins
|
| gptkbp:presentIn |
blood
tissues |
| gptkbp:structure |
monomer
|
| gptkbp:target |
gptkb:omalizumab
anti-IgE therapy |
| gptkbp:triggeredBy |
allergic inflammation
histamine release |
| gptkbp:usedIn |
diagnosis of allergies
immunotherapy monitoring |
| gptkbp:bfsParent |
gptkb:Xolair
|
| gptkbp:bfsLayer |
5
|