|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
BMPR-II
BRK-3
PPH1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
pulmonary arterial hypertension
|
|
gptkbp:discoveredBy
|
Genetic studies of pulmonary hypertension
|
|
gptkbp:encodes
|
BMPR2 protein
|
|
gptkbp:Entrez_Gene_ID
|
659
ENSG00000204217
|
|
gptkbp:expressedIn
|
gptkb:cancer
heart
vascular endothelium
|
|
gptkbp:firstDescribed
|
1998
|
|
gptkbp:fullName
|
bone morphogenetic protein receptor type II
|
|
gptkbp:function
|
serine/threonine kinase receptor
|
|
gptkbp:HGNC_ID
|
1078
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BMPR2
|
|
gptkbp:interactsWith
|
gptkb:BMP_ligands
|
|
gptkbp:length
|
1038 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
2q33-q34
|
|
gptkbp:memberOf
|
TGF-beta receptor superfamily
|
|
gptkbp:mutationAssociatedWith
|
heritable pulmonary arterial hypertension
idiopathic pulmonary arterial hypertension
|
|
gptkbp:OMIM
|
600799
|
|
gptkbp:orthologInMouse
|
Bmpr2
|
|
gptkbp:orthologInZebrafish
|
bmpr2a
bmpr2b
|
|
gptkbp:PDB
|
3G2F
|
|
gptkbp:product
|
cell surface receptor
|
|
gptkbp:type
|
gptkb:SMAD_pathway
non-SMAD pathways
|
|
gptkbp:UniProtID
|
Q13873
|
|
gptkbp:bfsParent
|
gptkb:bone_morphogenetic_proteins
|
|
gptkbp:bfsLayer
|
7
|