|
gptkbp:instanceOf
|
gptkb:protein
transcription factor
|
|
gptkbp:alias
|
gptkb:v-maf_avian_musculoaponeurotic_fibrosarcoma_oncogene_homolog
MAF
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:angioimmunoblastic_T-cell_lymphoma
multiple myeloma
|
|
gptkbp:binds
|
MARE (Maf recognition element)
|
|
gptkbp:contains
|
basic leucine zipper domain
|
|
gptkbp:discoveredBy
|
gptkb:T._Muramatsu
|
|
gptkbp:encodedBy
|
gptkb:MAF_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000178573
4099
|
|
gptkbp:expressedIn
|
gptkb:T_cells
gptkb:pancreatic_islets
lens of the eye
|
|
gptkbp:function
|
transcriptional activation
regulation of gene expression
|
|
gptkbp:HGNC_ID
|
6776
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
c-Maf
|
|
gptkbp:inhibitedBy
|
sumoylation
|
|
gptkbp:interactsWith
|
gptkb:CREB-binding_protein
gptkb:p300
|
|
gptkbp:length
|
373 amino acids
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
gptkb:16q23.2
|
|
gptkbp:memberOf
|
gptkb:Maf_family
|
|
gptkbp:molecularWeight
|
42 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Ayme-Gripp_syndrome
congenital cataracts
|
|
gptkbp:OMIM
|
177075
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
gptkb:4Y2A
|
|
gptkbp:phosphorylates
|
gptkb:JNK
gptkb:ERK
gptkb:GSK3
|
|
gptkbp:regulates
|
cell differentiation
immune response
Th2 cell differentiation
IL-10 expression
IL-17 expression
IL-21 expression
IL-22 expression
IL-4 expression
T follicular helper cell differentiation
regulatory T cell function
|
|
gptkbp:UniProtID
|
gptkb:O75444
|
|
gptkbp:bfsParent
|
gptkb:transcription_factor_Myb
|
|
gptkbp:bfsLayer
|
7
|