substance P

GPTKB entity

Statements (48)
Predicate Object
gptkbp:instanceOf neurotransmitter
peptide
gptkbp:affiliatedWith tachykinin peptide family
gptkbp:aminoAcidLength 11
gptkbp:associatedWith gptkb:depression
nausea
vomiting
anxiety
gptkbp:chemicalFormula C63H98N18O13S
gptkbp:discoveredBy gptkb:Ulf_von_Euler
gptkbp:discoveredIn 1931
gptkbp:encodedBy TAC1 gene
gptkbp:enemyOf gptkb:fosaprepitant
gptkb:aprepitant
netupitant
rolapitant
gptkbp:foundIn central nervous system
peripheral nervous system
gptkbp:function inflammation
mood regulation
pain transmission
https://www.w3.org/2000/01/rdf-schema#label substance P
gptkbp:involvedIn cell proliferation
wound healing
salivation
stress response
smooth muscle contraction
gastrointestinal motility
immune modulation
vasodilation
bronchoconstriction
immune cell activation
lacrimation
cardiovascular regulation
neurogenic inflammation
emesis
itch sensation
respiratory regulation
gptkbp:MeSH_ID D013362
gptkbp:PubChem_CID 16132397
CHEBI:16675
gptkbp:recipient neurokinin 1 receptor
gptkbp:sequence Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
gptkbp:UNII YRC47B5C40
gptkbp:bfsParent gptkb:prolyl_endopeptidase
gptkb:DPP-4_enzyme
gptkb:Membrane_metallo-endopeptidase
gptkbp:bfsLayer 7