Statements (48)
Predicate | Object |
---|---|
gptkbp:instanceOf |
neurotransmitter
peptide |
gptkbp:affiliatedWith |
tachykinin peptide family
|
gptkbp:aminoAcidLength |
11
|
gptkbp:associatedWith |
gptkb:depression
nausea vomiting anxiety |
gptkbp:chemicalFormula |
C63H98N18O13S
|
gptkbp:discoveredBy |
gptkb:Ulf_von_Euler
|
gptkbp:discoveredIn |
1931
|
gptkbp:encodedBy |
TAC1 gene
|
gptkbp:enemyOf |
gptkb:fosaprepitant
gptkb:aprepitant netupitant rolapitant |
gptkbp:foundIn |
central nervous system
peripheral nervous system |
gptkbp:function |
inflammation
mood regulation pain transmission |
https://www.w3.org/2000/01/rdf-schema#label |
substance P
|
gptkbp:involvedIn |
cell proliferation
wound healing salivation stress response smooth muscle contraction gastrointestinal motility immune modulation vasodilation bronchoconstriction immune cell activation lacrimation cardiovascular regulation neurogenic inflammation emesis itch sensation respiratory regulation |
gptkbp:MeSH_ID |
D013362
|
gptkbp:PubChem_CID |
16132397
CHEBI:16675 |
gptkbp:recipient |
neurokinin 1 receptor
|
gptkbp:sequence |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
|
gptkbp:UNII |
YRC47B5C40
|
gptkbp:bfsParent |
gptkb:prolyl_endopeptidase
gptkb:DPP-4_enzyme gptkb:Membrane_metallo-endopeptidase |
gptkbp:bfsLayer |
7
|