NK1

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs Neurokinin 1 receptor
gptkbp:encodedBy TACR1 gene
gptkbp:enemyOf gptkb:Aprepitant
Fosaprepitant
Netupitant
Rolapitant
gptkbp:expressedIn central nervous system
peripheral nervous system
immune cells
gptkbp:foundIn humans
other mammals
gptkbp:function involved in inflammation
involved in stress response
binds substance P
mediates pain transmission
https://www.w3.org/2000/01/rdf-schema#label NK1
gptkbp:ligand gptkb:neurokinin_A
gptkb:substance_P
gptkbp:locatedOnChromosome gptkb:chromosome_2p11.2
gptkbp:location gptkb:cell_membrane
gptkbp:medicalUse chemotherapy-induced nausea and vomiting
antiemetic therapy
gptkbp:recipient gptkb:G_protein-coupled_receptor
gptkbp:structure seven transmembrane domains
gptkbp:bfsParent gptkb:HL7_v2
gptkbp:bfsLayer 7