fosaprepitant

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:drug
antiemetic
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
gptkbp:ATCCode gptkb:A04AD12
gptkbp:CASNumber 172673-20-0
gptkbp:developedBy gptkb:Merck_&_Co.
gptkbp:eliminationHalfLife 2.3 hours (fosaprepitant), 9-13 hours (aprepitant)
gptkbp:excretion urine
feces
gptkbp:hasMolecularFormula C23H22F7N4O6P
https://www.w3.org/2000/01/rdf-schema#label fosaprepitant
gptkbp:KEGGID D04124
gptkbp:legalStatus prescription only
gptkbp:marketedAs gptkb:Emend
gptkbp:mechanismOfAction neurokinin-1 receptor antagonist
gptkbp:metabolism liver
gptkbp:pregnancyCategory B (US)
gptkbp:prodrugOf gptkb:aprepitant
gptkbp:PubChem_CID gptkb:CHEMBL1201197
11523702
9709632
DB06717
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect diarrhea
constipation
fatigue
headache
infusion site reactions
gptkbp:UNII 6Y7TQ9N1TB
gptkbp:usedFor prevention of chemotherapy-induced nausea and vomiting
gptkbp:bfsParent gptkb:Aprepitant
gptkbp:bfsLayer 7