Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
activated by proteolytic cleavage
|
| gptkbp:alsoKnownAs |
gptkb:matrix_metalloproteinase-3
|
| gptkbp:associatedWith |
gptkb:cardiovascular_disease
cancer progression rheumatoid arthritis |
| gptkbp:encodedBy |
MMP3 gene
|
| gptkbp:enzymeCommissionNumber |
EC 3.4.24.17
|
| gptkbp:family |
gptkb:matrix_metalloproteinase
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
degrades extracellular matrix proteins
involved in arthritis involved in tissue remodeling involved in wound healing |
| gptkbp:gene |
gptkb:MMP3
|
| https://www.w3.org/2000/01/rdf-schema#label |
stromelysin-1
|
| gptkbp:inhibitedBy |
tissue inhibitor of metalloproteinases (TIMP)
|
| gptkbp:location |
gptkb:chromosome_11q22.3
|
| gptkbp:molecularWeight |
54 kDa (proenzyme)
|
| gptkbp:OMIM |
185250
|
| gptkbp:structure |
contains zinc-binding motif
|
| gptkbp:substrate |
gptkb:fibronectin
gptkb:collagen_type_IV gptkb:laminin gelatin collagen type IX |
| gptkbp:UniProtID |
gptkb:P08254
|
| gptkbp:bfsParent |
gptkb:MMP3
|
| gptkbp:bfsLayer |
7
|