|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
resveratrol
|
|
gptkbp:alternativeName
|
gptkb:SIR2L2
NAD-dependent protein deacetylase sirtuin-2
SIR2-like protein 2
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:cancer
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:SIRT2
|
|
gptkbp:enzymeClassification
|
gptkb:EC_3.5.1.98
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:testis
brain
heart
liver
pancreas
|
|
gptkbp:family
|
sirtuin family
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:NAD-dependent_deacetylase
regulation of cell cycle
regulation of microtubule dynamics
|
|
gptkbp:gene
|
gptkb:SIRT2
|
|
gptkbp:HGNC_ID
|
14931
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
sirtuin 2
|
|
gptkbp:inhibitedBy
|
gptkb:AGK2
gptkb:SirReal2
|
|
gptkbp:interactsWith
|
gptkb:FOXO3
gptkb:p53
gptkb:alpha-tubulin
|
|
gptkbp:length
|
389 amino acids
|
|
gptkbp:locatedOnChromosome
|
19q13.32
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:OMIM
|
604144
|
|
gptkbp:orthologInMouse
|
gptkb:Sirt2
|
|
gptkbp:PDB
|
1J8F
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:related_to_process
|
aging
metabolism
neurodegeneration
tumorigenesis
|
|
gptkbp:UniProtID
|
Q8IXJ6
|
|
gptkbp:bfsParent
|
gptkb:SIRT2
|
|
gptkbp:bfsLayer
|
8
|