Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:sirtuin_inhibitor |
| gptkbp:CASNumber |
304896-28-4
|
| gptkbp:criteria |
selective for SIRT2 over SIRT1 and SIRT3
|
| gptkbp:effect |
inhibits deacetylation activity of SIRT2
|
| gptkbp:hasMolecularFormula |
C14H13N3O2S
|
| gptkbp:IUPACName |
2-cyano-3-[5-(2,5-dimethylphenyl)furan-2-yl]-N-(2-methylphenyl)acrylamide
|
| gptkbp:PubChem_CID |
11364422
CHEMBL1809902 |
| gptkbp:studiedBy |
gptkb:Parkinson's_disease
gptkb:Huntington's_disease |
| gptkbp:synonym |
AGK-2
SIRT2 inhibitor AGK2 |
| gptkbp:target |
gptkb:SIRT2
|
| gptkbp:bfsParent |
gptkb:SIRT2
gptkb:AG+89 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
AGK2
|