|
gptkbp:instanceOf
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gptkb:receptor_tyrosine_kinase
gptkb:protein
|
|
gptkbp:binds
|
gptkb:adenosine_triphosphate
gptkb:adenosine
gptkb:adenosine_diphosphate
guanosine triphosphate
|
|
gptkbp:discoveredBy
|
gptkb:Geoffrey_Burnstock
|
|
gptkbp:encodedBy
|
various genes
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:nervous_system
gptkb:kidney
heart
gastrointestinal tract
liver
endothelial cells
immune cells
smooth muscle
|
|
gptkbp:firstDescribed
|
1970s
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
purinergic receptors
|
|
gptkbp:involvedIn
|
inflammation
immune response
neurotransmission
pain perception
vasodilation
platelet aggregation
|
|
gptkbp:modulatedBy
|
gptkb:theophylline
caffeine
antagonists
agonists
adenosine analogs
|
|
gptkbp:P1_receptor_binds
|
gptkb:adenosine
|
|
gptkbp:P2_receptor_binds
|
gptkb:ATP
|
|
gptkbp:P2_receptor_subtype
|
P2X receptor
P2Y receptor
|
|
gptkbp:P2X_receptor_type
|
gptkb:voltage-gated_potassium_channel
|
|
gptkbp:P2Y_receptor_type
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:relatedTo
|
nucleotides
nucleosides
purines
|
|
gptkbp:significance
|
gptkb:cancer
cardiovascular diseases
inflammatory diseases
neurological disorders
chronic pain
|
|
gptkbp:subclassOf
|
cell surface receptor
|
|
gptkbp:subspecies
|
P1 receptor
P2 receptor
|
|
gptkbp:bfsParent
|
gptkb:Class_A_(Rhodopsin-like)
|
|
gptkbp:bfsLayer
|
6
|