|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
SCDGF
platelet-derived growth factor C
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
fibrosis
|
|
gptkbp:biologicalProcess
|
cell proliferation
wound healing
angiogenesis
|
|
gptkbp:discoveredBy
|
2001
|
|
gptkbp:encodes
|
platelet derived growth factor C protein
|
|
gptkbp:Entrez_Gene_ID
|
56034
ENSG00000145431
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
platelet derived growth factor C
|
|
gptkbp:function
|
cell proliferation
angiogenesis
growth factor activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOMolecularFunction
|
receptor binding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:28998
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PDGFC
|
|
gptkbp:interactsWith
|
gptkb:PDGFR-beta
gptkb:PDGFR-alpha
|
|
gptkbp:length
|
345 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_4
4q32
|
|
gptkbp:molecularWeight
|
39 kDa
|
|
gptkbp:OMIM
|
607402
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pdgfc
|
|
gptkbp:postTranslationalModification
|
proteolytic cleavage
|
|
gptkbp:proteinFamily
|
gptkb:CUB_domain
PDGF/VEGF domain
|
|
gptkbp:RefSeq
|
NM_016205
|
|
gptkbp:regulates
|
regulated by TGF-beta
upregulated in tumors
|
|
gptkbp:relatedTo
|
PDGF family
|
|
gptkbp:subcellularLocation
|
secreted
|
|
gptkbp:UniProtID
|
Q9NRA1
|
|
gptkbp:bfsParent
|
gptkb:Platelet-derived_growth_factor
|
|
gptkbp:bfsLayer
|
6
|