mitogen-activated protein kinase pathways
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
signaling molecule
|
| gptkbp:activatedBy |
stress
cytokines growth factors |
| gptkbp:alsoKnownAs |
MAPK pathways
|
| gptkbp:component |
gptkb:MAP_kinase_kinase
gptkb:MAP_kinase_kinase_kinase MAP kinase |
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:foundIn |
eukaryotes
|
| https://www.w3.org/2000/01/rdf-schema#label |
mitogen-activated protein kinase pathways
|
| gptkbp:includes |
gptkb:ERK_pathway
gptkb:JNK_pathway gptkb:p38_MAPK_pathway |
| gptkbp:inhibitedBy |
MAPK inhibitors
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation cell survival gene expression |
| gptkbp:studiedIn |
gptkb:yeast
mammals plants |
| gptkbp:bfsParent |
gptkb:c-Jun_N-terminal_kinase_pathway
|
| gptkbp:bfsLayer |
7
|