mechanistic target of rapamycin complex 2
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:mTORC2
|
| gptkbp:component |
gptkb:DEPTOR
gptkb:PROTOR1 gptkb:PROTOR2 gptkb:RICTOR gptkb:mLST8 gptkb:mSIN1 gptkb:mTOR |
| gptkbp:discoveredBy |
2004
|
| gptkbp:function |
regulation of cell proliferation
regulation of cell survival regulation of cytoskeleton regulation of metabolism |
| https://www.w3.org/2000/01/rdf-schema#label |
mechanistic target of rapamycin complex 2
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:phosphorylates |
gptkb:PKCĪ±
gptkb:SGK1 gptkb:AKT |
| gptkbp:regulates |
lipid metabolism
cell migration cell survival signaling actin cytoskeleton |
| gptkbp:relatedTo |
gptkb:mechanistic_target_of_rapamycin_complex_1
|
| gptkbp:sensitivity |
rapamycin (indirectly)
|
| gptkbp:bfsParent |
gptkb:mTORC2
|
| gptkbp:bfsLayer |
6
|