Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:GBL
gptkb:GβL gptkb:mammalian_lethal_with_SEC13_protein_8 |
| gptkbp:binds |
gptkb:mTOR
|
| gptkbp:component |
gptkb:mTORC1
gptkb:mTORC2 |
| gptkbp:discoveredIn |
2002
|
| gptkbp:encodedBy |
gptkb:MLST8_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
signal transduction
regulation of mTOR kinase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
mLST8
|
| gptkbp:interactsWith |
gptkb:RICTOR
gptkb:RPTOR gptkb:SIN1 |
| gptkbp:involvedIn |
gptkb:PI3K-Akt_signaling_pathway
cell proliferation cell growth autophagy metabolism regulation |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_16p13.3
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
36 kDa
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:PDB |
gptkb:5FLC
4JSV |
| gptkbp:requires |
mTORC1 stability
mTORC2 assembly |
| gptkbp:structure |
WD40 repeat protein
|
| gptkbp:UniProtID |
gptkb:Q9BVC4
|
| gptkbp:bfsParent |
gptkb:mTOR_pathway
|
| gptkbp:bfsLayer |
5
|