|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:GBL
gptkb:GβL
gptkb:mammalian_lethal_with_SEC13_protein_8
|
|
gptkbp:binds
|
gptkb:mTOR
|
|
gptkbp:component
|
gptkb:mTORC1
gptkb:mTORC2
|
|
gptkbp:discoveredIn
|
2002
|
|
gptkbp:encodedBy
|
gptkb:MLST8_gene
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
regulation of mTOR kinase activity
|
|
gptkbp:interactsWith
|
gptkb:RICTOR
gptkb:RPTOR
gptkb:SIN1
|
|
gptkbp:involvedIn
|
gptkb:PI3K-Akt_signaling_pathway
cell proliferation
cell growth
autophagy
metabolism regulation
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_16p13.3
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
36 kDa
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
gptkb:5FLC
4JSV
|
|
gptkbp:requires
|
mTORC1 stability
mTORC2 assembly
|
|
gptkbp:structure
|
WD40 repeat protein
|
|
gptkbp:UniProtID
|
gptkb:Q9BVC4
|
|
gptkbp:bfsParent
|
gptkb:mTORC1
gptkb:mTORC2
gptkb:mTOR_pathway
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mLST8
|