|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:Avo3_homolog
gptkb:FLJ23571
gptkb:mKIAA1001
|
|
gptkbp:complexity
|
gptkb:mTORC2
|
|
gptkbp:discoveredIn
|
2004
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000164327
253260
|
|
gptkbp:fullName
|
gptkb:Rapamycin-insensitive_companion_of_mTOR
|
|
gptkbp:function
|
regulates metabolism
regulates cell survival
component of mTORC2 complex
regulates cell migration
regulates cytoskeleton
|
|
gptkbp:gene
|
gptkb:RICTOR_gene
|
|
gptkbp:interactsWith
|
gptkb:mLST8
gptkb:mTOR
gptkb:PROTOR
gptkb:SIN1
|
|
gptkbp:involvedIn
|
gptkb:PI3K/AKT_signaling_pathway
cancer progression
cell growth
insulin signaling
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
insulin resistance
metabolic disorders
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Drosophila_melanogaster
|
|
gptkbp:phosphorylates
|
gptkb:AKT
|
|
gptkbp:regulates
|
AKT phosphorylation
PKCα phosphorylation
SGK1 phosphorylation
|
|
gptkbp:requires
|
mTORC2 activity
|
|
gptkbp:sensitivity
|
gptkb:rapamycin
|
|
gptkbp:UniProtID
|
Q6R327
|
|
gptkbp:bfsParent
|
gptkb:mTORC2
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RICTOR
|