Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:IL6R
IL-6 receptor alpha |
| gptkbp:binds |
gptkb:interleukin-6
|
| gptkbp:encodedBy |
gptkb:IL6R_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
gptkb:hepatocytes gptkb:B_cells gptkb:T_cells macrophages monocytes neutrophils |
| gptkbp:formsComplexWith |
gptkb:gp130
|
| gptkbp:foundIn |
cell surface
|
| gptkbp:function |
mediates IL-6 signaling
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD126
|
| gptkbp:involvedIn |
inflammation
immune response |
| gptkbp:isSolubleIn |
sIL-6R
|
| gptkbp:locatedOnChromosome |
1q21
|
| gptkbp:target |
gptkb:tocilizumab
gptkb:sarilumab |
| gptkbp:bfsParent |
gptkb:interleukin-6_receptor
gptkb:IL-6_receptor |
| gptkbp:bfsLayer |
7
|