|
gptkbp:instanceOf
|
gptkb:protein
cell surface receptor
|
|
gptkbp:alternativeSplicing
|
soluble IL-4R
|
|
gptkbp:associatedWith
|
asthma
immunodeficiency
allergic diseases
|
|
gptkbp:binds
|
gptkb:interleukin-4
gptkb:interleukin-13
|
|
gptkbp:EC_number
|
none (not an enzyme)
|
|
gptkbp:encodedBy
|
gptkb:IL4R_gene
|
|
gptkbp:Entrez_Gene_ID
|
IL4R
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:T_cells
gptkb:basophils
gptkb:mast_cells
macrophages
endothelial cells
fibroblasts
epithelial cells
|
|
gptkbp:foundIn
|
humans
mice
other mammals
|
|
gptkbp:HGNC_ID
|
6015
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
interleukin-4 receptor
|
|
gptkbp:involvedIn
|
gptkb:JAK-STAT_signaling_pathway
immune response
allergic inflammation
|
|
gptkbp:locatedIn
|
gptkb:plasma_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p12.1
|
|
gptkbp:modulatedBy
|
B cell differentiation
macrophage activation
IgE production
|
|
gptkbp:molecularWeight
|
approximately 140 kDa
|
|
gptkbp:OMIM
|
147780
|
|
gptkbp:PDB
|
3BPN
3BPO
1IAR
3BPG
3BPH
3BPI
3BPK
3BPL
3BPM
3BPP
|
|
gptkbp:subunit
|
gptkb:IL-13Rα1
gptkb:IL-4Rα
gptkb:common_gamma_chain
|
|
gptkbp:target
|
gptkb:dupilumab
|
|
gptkbp:UniProtID
|
gptkb:P24394
|
|
gptkbp:bfsParent
|
gptkb:common_gamma_chain
gptkb:interleukin-4
gptkb:IL2RG
|
|
gptkbp:bfsLayer
|
7
|