|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
asthma
allergic diseases
|
|
gptkbp:binds
|
gptkb:Interleukin-13
Interleukin-4
|
|
gptkbp:component
|
gptkb:IL-4_receptor
|
|
gptkbp:encodedBy
|
gptkb:IL4R_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000113520
3566
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:T_cells
macrophages
immune cells
|
|
gptkbp:formsComplexWith
|
gptkb:IL-13Rα1
IL-2Rγ
|
|
gptkbp:fullName
|
Interleukin-4 receptor alpha chain
|
|
gptkbp:function
|
regulates immune response
mediates IL-4 and IL-13 signaling
|
|
gptkbp:gene
|
IL4R
|
|
gptkbp:HGNC_ID
|
6015
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL-4Rα
|
|
gptkbp:inhibitedBy
|
gptkb:dupilumab
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p12.1
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
approximately 80 kDa
|
|
gptkbp:OMIM
|
147780
|
|
gptkbp:postTranslationalModification
|
glycosylation
|
|
gptkbp:targetOfDrug
|
gptkb:atopic_dermatitis
asthma
|
|
gptkbp:type
|
gptkb:JAK-STAT_pathway
|
|
gptkbp:UniProtID
|
gptkb:P24394
|
|
gptkbp:bfsParent
|
gptkb:IL-4_receptor
|
|
gptkbp:bfsLayer
|
7
|