|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
CD124
IL-4R
interleukin-4 receptor alpha chain
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
asthma
immunodeficiency
allergic diseases
|
|
gptkbp:discoveredBy
|
researchers in immunology
|
|
gptkbp:encodes
|
interleukin-4 receptor alpha chain
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000113520
3566
|
|
gptkbp:expressedIn
|
gptkb:cancer
spleen
immune cells
|
|
gptkbp:fullName
|
interleukin 4 receptor
|
|
gptkbp:function
|
cytokine receptor activity
interleukin-13 binding
interleukin-4 binding
|
|
gptkbp:HGNC_ID
|
6015
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL4R gene
|
|
gptkbp:interactsWith
|
gptkb:IL13
gptkb:IL4
gptkb:JAK1
gptkb:STAT6
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p12.1
16
|
|
gptkbp:mutationAssociatedWith
|
atopy
hyper-IgE syndrome
|
|
gptkbp:OMIM
|
147781
|
|
gptkbp:orthologInMouse
|
Il4ra
|
|
gptkbp:pathway
|
gptkb:JAK-STAT_signaling_pathway
immune response
|
|
gptkbp:product
|
IL4Rα
|
|
gptkbp:significance
|
target for allergy treatment
target for asthma therapy
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
gptkb:P24394
|
|
gptkbp:bfsParent
|
gptkb:IL-4_receptor
|
|
gptkbp:bfsLayer
|
7
|