|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD213A1
|
|
gptkbp:associatedWith
|
asthma
allergic inflammation
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:encodedBy
|
IL13RA1 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136111
3597
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
liver
immune cells
|
|
gptkbp:formsComplexWith
|
gptkb:IL-4Rα
gptkb:IL-13
IL-13Rα2
|
|
gptkbp:fullName
|
Interleukin-13 receptor subunit alpha-1
|
|
gptkbp:function
|
binds interleukin-13
receptor for interleukin-13
forms receptor complex with IL-4Rα
|
|
gptkbp:gene
|
gptkb:IL13RA1
|
|
gptkbp:HGNC_ID
|
5977
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IL-13Rα1
|
|
gptkbp:locatedOnChromosome
|
gptkb:Xq24
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~50 kDa
|
|
gptkbp:OMIM
|
604127
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:participatedIn
|
gptkb:JAK-STAT_signaling_pathway
|
|
gptkbp:PDB
|
4PSJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NM_001560
|
|
gptkbp:relatedTo
|
gptkb:interleukin-4
gptkb:IL-4_receptor
gptkb:interleukin-13
IL-13Rα2
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:type
|
activates JAK1
activates STAT6
activates TYK2
|
|
gptkbp:UniProtID
|
gptkb:Q14626
|
|
gptkbp:bfsParent
|
gptkb:IL-4_receptor
|
|
gptkbp:bfsLayer
|
7
|