|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CD29
fibronectin receptor beta subunit
|
|
gptkbp:associatedWith
|
gptkb:cancer
cardiomyopathy
muscular dystrophy
fibrosis
|
|
gptkbp:biologicalProcess
|
angiogenesis
immune response
integrin-mediated signaling pathway
cell-matrix adhesion
|
|
gptkbp:component
|
integrin receptor
|
|
gptkbp:discoveredBy
|
1986
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ITGB1
ENSG00000150093
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:formsHeterodimerWith
|
integrin alpha subunits
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
cell adhesion
|
|
gptkbp:gene
|
gptkb:ITGB1
|
|
gptkbp:HGNC_ID
|
6153
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
integrin beta-1
|
|
gptkbp:interactsWith
|
gptkb:fibronectin
gptkb:talin
gptkb:laminin
collagen
focal adhesion kinase
vitronectin
tenascin
kindlin
|
|
gptkbp:involvedIn
|
embryonic development
wound healing
cell migration
extracellular matrix organization
|
|
gptkbp:length
|
798 amino acids
|
|
gptkbp:locatedOnChromosome
|
10p11.21
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
88 kDa
|
|
gptkbp:OMIM
|
135630
|
|
gptkbp:PDB
|
3VI3
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NP_002202.2
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
P05556
|
|
gptkbp:bfsParent
|
gptkb:alpha-4_beta-1_integrin
|
|
gptkbp:bfsLayer
|
7
|