ITGB1

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias CD29
FNRB
GPIIA
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:cancer
muscular dystrophy
fibrosis
gptkbp:biologicalProcess wound healing
angiogenesis
cell migration
extracellular matrix organization
integrin binding
gptkbp:discoveredBy Tamkun et al.
gptkbp:discoveredIn 1986
gptkbp:encodes Integrin beta-1 protein
gptkbp:Entrez_Gene_ID 3688
ENSG00000150093
gptkbp:expressedIn many tissues
gptkbp:fullName integrin subunit beta 1
gptkbp:function signal transduction
cell adhesion
gptkbp:GOID GO:0007155
GO:0008305
GO:0007160
gptkbp:hasTranscriptVariant multiple
gptkbp:HGNC_ID HGNC:6153
https://www.w3.org/2000/01/rdf-schema#label ITGB1
gptkbp:interactsWith gptkb:ITGA4
gptkb:ITGA1
ITGA2
ITGA3
ITGA5
ITGA6
ITGA7
ITGA9
ITGAV
gptkbp:length 798 amino acids
gptkbp:locatedOnChromosome gptkb:chromosome_10
gptkbp:molecularWeight 88 kDa
gptkbp:OMIM 135630
gptkbp:orthologInMouse Itgb1
gptkbp:orthologInZebrafish itgb1b.1
gptkbp:postTranslationalModification phosphorylation
glycosylation
gptkbp:proteinFamily integrin beta chain family
gptkbp:subcellularLocation gptkb:cell_membrane
focal adhesion
gptkbp:UniProtID P05556
gptkbp:bfsParent gptkb:alpha-4_beta-1_integrin
gptkbp:bfsLayer 7