Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
TLN1
TLN2 |
gptkbp:discoveredBy |
Burridge and Connell
|
gptkbp:discoveredIn |
1983
|
gptkbp:encodedBy |
TLN1 gene
TLN2 gene |
gptkbp:foundIn |
focal adhesions
|
gptkbp:function |
links integrins to actin cytoskeleton
|
https://www.w3.org/2000/01/rdf-schema#label |
talin
|
gptkbp:interactsWith |
gptkb:actin
gptkb:vinculin integrin beta subunits |
gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
gptkbp:molecularWeight |
~270 kDa
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:role |
cell migration
cell adhesion mechanotransduction |
gptkbp:structure |
contains FERM domain
contains rod domain |
gptkbp:bfsParent |
gptkb:PTK2
|
gptkbp:bfsLayer |
6
|