talin

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName TLN1
TLN2
gptkbp:discoveredBy Burridge and Connell
gptkbp:discoveredIn 1983
gptkbp:encodedBy TLN1 gene
TLN2 gene
gptkbp:foundIn focal adhesions
gptkbp:function links integrins to actin cytoskeleton
https://www.w3.org/2000/01/rdf-schema#label talin
gptkbp:interactsWith gptkb:actin
gptkb:vinculin
integrin beta subunits
gptkbp:locale gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:molecularWeight ~270 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:role cell migration
cell adhesion
mechanotransduction
gptkbp:structure contains FERM domain
contains rod domain
gptkbp:bfsParent gptkb:PTK2
gptkbp:bfsLayer 6