insulin-like growth factor 1

URI: https://gptkb.org/entity/insulin-like_growth_factor_1
GPTKB entity
Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:IGF-1
gptkbp:associatedWith gptkb:cancer
gptkb:Laron_syndrome
growth disorders
gptkbp:binds gptkb:IGF-1_receptor
gptkbp:category growth factor
hormone
gptkbp:Entrez_Gene_ID 3479
gptkbp:function inhibits apoptosis
promotes cell growth
promotes cell differentiation
gptkbp:gene gptkb:IGF1
gptkbp:hgncID gptkb:HGNC:5464
https://www.w3.org/2000/01/rdf-schema#label insulin-like growth factor 1
gptkbp:locatedOnChromosome chromosome 12q23.2
gptkbp:medicalUse biomarker for acromegaly
biomarker for growth hormone deficiency
gptkbp:PDB 1IMX
gptkbp:producedBy liver
peripheral tissues
gptkbp:promotion recombinant human growth hormone
gptkbp:regulates regulated by nutritional status
regulated by age
regulated by sex hormones
regulated by thyroid hormones
gptkbp:relatedTo gptkb:insulin-like_growth_factor_2
gptkb:insulin
gptkbp:sequence 70 amino acids
gptkbp:structure single-chain polypeptide
gptkbp:UniProtID P05019
gptkbp:bfsParent gptkb:IGF1_receptor
gptkb:insulin-like_growth_factor_2
gptkb:somatomedin-A
gptkb:insulin-like_growth_factor_1_receptor
gptkbp:bfsLayer 7