Heterogeneous nuclear ribonucleoprotein A1
GPTKB entity
Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:hnRNP_A1
heterogeneous nuclear ribonucleoprotein core protein A1 |
| gptkbp:associatedWith |
gptkb:multisystem_proteinopathy
amyotrophic lateral sclerosis |
| gptkbp:biologicalProcess |
regulation of gene expression
alternative splicing mRNA export from nucleus |
| gptkbp:Entrez_Gene_ID |
ENSP00000354825
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
RNA binding
mRNA transport pre-mRNA processing |
| gptkbp:gene |
gptkb:HNRNPA1
|
| gptkbp:hasIsoform |
hnRNP A1A
hnRNP A1B |
| gptkbp:interactsWith |
gptkb:SRSF1
gptkb:HNRNPA2B1 |
| gptkbp:involves |
neurodegenerative diseases
DNA damage response viral replication HIV-1 RNA metabolism stress granule formation |
| gptkbp:length |
372 amino acids
|
| gptkbp:locatedOnChromosome |
12q13.13
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~34 kDa
|
| gptkbp:OMIM |
164017
|
| gptkbp:PDB |
gptkb:1HA1
|
| gptkbp:postTranslationalModification |
phosphorylation
methylation |
| gptkbp:RefSeq |
NP_002127.1
|
| gptkbp:regulates |
gptkb:translator
apoptosis cell proliferation telomere maintenance RNA stability |
| gptkbp:structure |
contains two RNA recognition motifs (RRMs)
glycine-rich C-terminal domain |
| gptkbp:subcellularLocation |
shuttles between nucleus and cytoplasm
|
| gptkbp:UniProtID |
gptkb:P09651
|
| gptkbp:bfsParent |
gptkb:hnRNPA1
gptkb:HNRNPA1 |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Heterogeneous nuclear ribonucleoprotein A1
|