Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:4E-BP1
gptkb:PHAS-I |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:binds |
gptkb:eIF4E
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000187840
1978 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of translation initiation
|
| gptkbp:gene |
gptkb:EIF4EBP1
|
| gptkbp:HGNC_ID |
gptkb:HGNC:3288
|
| https://www.w3.org/2000/01/rdf-schema#label |
eIF4E-binding protein 1
|
| gptkbp:inhibitedBy |
cap-dependent translation
|
| gptkbp:involves |
gptkb:mTOR_signaling_pathway
|
| gptkbp:locatedOnChromosome |
gptkb:8p12
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
12 kDa
|
| gptkbp:orthologInMouse |
Eif4ebp1
|
| gptkbp:PDB |
1EJ1
|
| gptkbp:phosphorylates |
gptkb:mTOR
Ser65 Thr37 Thr46 Thr70 |
| gptkbp:RefSeq |
gptkb:NM_004095
|
| gptkbp:regulates |
protein synthesis
phosphorylation-dependent |
| gptkbp:UniProtID |
gptkb:Q13541
|
| gptkbp:bfsParent |
gptkb:4EBP1
|
| gptkbp:bfsLayer |
6
|