cytochrome P450 family 2 subfamily D member 6

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:alternativeName	gptkb:CYP2D6 gptkb:cytochrome_P450_2D6 gptkb:debrisoquine_4-hydroxylase
gptkbp:associatedWith	adverse drug reactions variable drug response poor metabolizer phenotype ultrarapid metabolizer phenotype
gptkbp:encodedBy	gptkb:CYP2D6_gene
gptkbp:enzymeCommissionNumber	1.14.14.1
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	drug metabolism oxidation of xenobiotics hydroxylation of drugs
gptkbp:hasPolymorphism	highly polymorphic
gptkbp:HGNC_ID	2593
https://www.w3.org/2000/01/rdf-schema#label	cytochrome P450 family 2 subfamily D member 6
gptkbp:locatedIn	gptkb:endoplasmic_reticulum
gptkbp:locatedOnChromosome	gptkb:chromosome_22q13.2
gptkbp:memberOf	gptkb:cytochrome_P450_superfamily gptkb:CYP2D_subfamily
gptkbp:metabolism	gptkb:codeine gptkb:tamoxifen beta blockers opioids antipsychotics antidepressants
gptkbp:OMIM	124030
gptkbp:product	gptkb:CYP2D6
gptkbp:significance	pharmacogenomics
gptkbp:UniProtID	P10635
gptkbp:bfsParent	gptkb:CYP2D6
gptkbp:bfsLayer	5