Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:CYP2D6
|
| gptkbp:associatedWith |
poor metabolizer phenotype
|
| gptkbp:catalyzes |
hydroxylation of debrisoquine
|
| gptkbp:cofactor |
hemoglobin
NADPH |
| gptkbp:EC_number |
1.14.14.1
|
| gptkbp:enzymeClassification |
gptkb:cytochrome_P450
|
| gptkbp:gene |
gptkb:CYP2D6
|
| gptkbp:hasPolymorphism |
affects drug response
|
| https://www.w3.org/2000/01/rdf-schema#label |
debrisoquine 4-hydroxylase
|
| gptkbp:involvedIn |
drug metabolism
|
| gptkbp:locatedIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:locatedOnChromosome |
gptkb:22q13.2
|
| gptkbp:OMIM |
124030
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:substrate |
gptkb:tricyclic_antidepressants
gptkb:codeine gptkb:debrisoquine gptkb:tamoxifen |
| gptkbp:UniProtID |
P10635
|
| gptkbp:bfsParent |
gptkb:CYP2D6
|
| gptkbp:bfsLayer |
5
|