cyclin-dependent kinase inhibitor 2A
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
gptkb:ARF
gptkb:CDK4I gptkb:INK4A gptkb:MTS1 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:familial_melanoma
gptkb:glioblastoma melanoma pancreatic cancer |
| gptkbp:encodes |
gptkb:p14ARF
gptkb:p16INK4a |
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000147889
1029 |
| gptkbp:expressedIn |
gptkb:nucleus
|
| gptkbp:function |
tumor suppressor
|
| gptkbp:HGNC_ID |
HGNC:1787
|
| https://www.w3.org/2000/01/rdf-schema#label |
cyclin-dependent kinase inhibitor 2A
|
| gptkbp:inhibitedBy |
gptkb:CDK4
gptkb:CDK6 |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9
gptkb:9p21 |
| gptkbp:mutationAssociatedWith |
increased cancer risk
|
| gptkbp:OMIM |
600160
|
| gptkbp:orthologInMouse |
gptkb:Cdkn2a
|
| gptkbp:regulates |
cell cycle
|
| gptkbp:symbol |
gptkb:CDKN2A
|
| gptkbp:UniProtID |
gptkb:P42771
|
| gptkbp:bfsParent |
gptkb:p16INK4a
gptkb:p16 gptkb:INK4A |
| gptkbp:bfsLayer |
7
|