Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:CDKN2A
gptkb:cyclin-dependent_kinase_inhibitor_2A |
| gptkbp:associatedWith |
tumor suppression
|
| gptkbp:discoveredIn |
1994
|
| gptkbp:encodes |
gptkb:p14ARF
gptkb:p16INK4A |
| gptkbp:Entrez_Gene_ID |
1029
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:geneType |
tumor suppressor
|
| gptkbp:hasTranscriptVariant |
gptkb:p14ARF
gptkb:p16INK4A |
| gptkbp:HGNC_ID |
1787
|
| https://www.w3.org/2000/01/rdf-schema#label |
INK4A
|
| gptkbp:inhibitedBy |
gptkb:CDK4
gptkb:CDK6 |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9
gptkb:9p21 |
| gptkbp:lossOfFunctionLeadsTo |
uncontrolled cell proliferation
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:glioblastoma melanoma pancreatic cancer bladder cancer |
| gptkbp:OMIM |
600160
|
| gptkbp:orthologInMouse |
gptkb:Cdkn2a
|
| gptkbp:partOfPathway |
Rb pathway
|
| gptkbp:regulates |
cell cycle
G1 phase of cell cycle |
| gptkbp:UniProtID |
gptkb:P42771
|
| gptkbp:bfsParent |
gptkb:CDKN2A
|
| gptkbp:bfsLayer |
6
|