Statements (100)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:catalyzes |
hydroxylation of small organic molecules
|
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:Entrez_Gene_ID |
1571
ENSG00000130649 |
| gptkbp:enzymeClassification |
gptkb:EC_1.14.14.1
|
| gptkbp:function |
metabolism of xenobiotics
monooxygenase |
| gptkbp:gene |
CYP2E1
|
| gptkbp:hasPolymorphism |
present
|
| gptkbp:HGNC_ID |
2597
|
| https://www.w3.org/2000/01/rdf-schema#label |
P07550
|
| gptkbp:inducedBy |
gptkb:acetone
ethanol |
| gptkbp:involves |
drug metabolism
activation of procarcinogens metabolism of fatty acids |
| gptkbp:length |
493
|
| gptkbp:locatedOnChromosome |
10
|
| gptkbp:location |
10q26.3
|
| gptkbp:molecularWeight |
56574
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
metabolism
drug metabolism - cytochrome P450 metabolism of xenobiotics by cytochrome P450 chemical carcinogenesis |
| gptkbp:PDB |
3E4E
3E4F 3E4G 3E4H 3E4I 3E4J 3E4K 3E4L 3E4M 3E4N 3E4O 3E4P 3E4Q 3E4R 3E4S 3E4T 3E4U 3E4V 3E4W 3E4X 3E4Y 3E4Z 3E50 3E51 3E52 3E53 3E54 3E55 3E56 3E57 3E58 3E59 3E5A 3E5B 3E5C 3E5D 3E5E 3E5F 3E5G 3E5H 3E5I 3E5J 3E5K 3E5L 3E5M 3E5N 3E5O 3E5P 3E5Q 3E5R 3E5S 3E5T 3E5U 3E5V 3E5W 3E5X 3E5Y 3E5Z 3E6I 3GPH 3KOH 3T3Z |
| gptkbp:protein_name |
Cytochrome P450 2E1
|
| gptkbp:RefSeq |
NP_000763.2
|
| gptkbp:subcellularLocation |
gptkb:endoplasmic_reticulum
microsome |
| gptkbp:tissue_specificity |
gptkb:cancer
gptkb:kidney liver |
| gptkbp:UniProtID |
gptkb:P07550
|
| gptkbp:bfsParent |
gptkb:ADRB2_gene
gptkb:beta-2_adrenergic_receptor |
| gptkbp:bfsLayer |
7
|