Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:apoptosome
|
| gptkbp:alsoKnownAs |
gptkb:caspase-9
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:cleavage |
gptkb:caspase-3
gptkb:caspase-7 |
| gptkbp:discoveredBy |
1997
|
| gptkbp:encodedBy |
CASP9 gene
|
| gptkbp:enzymeClassification |
EC 3.4.22.62
|
| gptkbp:function |
initiator caspase in apoptosis
|
| gptkbp:GO_term |
GO:0006915 (apoptotic process)
|
| gptkbp:inhibitedBy |
gptkb:XIAP
|
| gptkbp:involvedIn |
intrinsic apoptotic signaling pathway
|
| gptkbp:locatedOnChromosome |
gptkb:1p36.21
|
| gptkbp:molecularWeight |
46 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:structure |
contains CARD domain
|
| gptkbp:subcellularLocation |
cytosol
|
| gptkbp:UniProtID |
gptkb:P55211
|
| gptkbp:bfsParent |
gptkb:CASP9
|
| gptkbp:bfsLayer |
8
|
| http://www.w3.org/2000/01/rdf-schema#label |
apoptotic protease Mch-6
|