|
gptkbp:instanceOf
|
gptkb:UniProt_accession_number
|
|
gptkbp:alternativeName
|
gptkb:CPP32
Apaf-3
Apoptotic protease Mch-6
CASP-9
ICE-like apoptotic protease 6
|
|
gptkbp:amendedBy
|
Phosphorylation
Cleavage
|
|
gptkbp:associatedWith
|
gptkb:Melanoma
gptkb:Glioblastoma
gptkb:Colorectal_cancer
gptkb:Neuroblastoma
Acute myeloid leukemia
|
|
gptkbp:biologicalProcess
|
Proteolysis
Apoptotic process
Cell death
Cysteine-type endopeptidase activity
|
|
gptkbp:cofactor
|
gptkb:Calcium
Magnesium
|
|
gptkbp:database
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000132906
842
|
|
gptkbp:enzymeClassification
|
EC 3.4.22.62
|
|
gptkbp:function
|
Involved in the activation cascade of caspases responsible for apoptosis execution
|
|
gptkbp:gene
|
gptkb:CASP9
|
|
gptkbp:hasIsoform
|
5
|
|
gptkbp:HGNC_ID
|
HGNC:1509
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:locusType
|
1q22-q23
|
|
gptkbp:mass
|
46,000 Da
|
|
gptkbp:OMIM
|
602234
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
Apoptosis
Intrinsic apoptotic signaling pathway
|
|
gptkbp:PDB
|
gptkb:1QTN
gptkb:2AR9
1JXQ
1NW9
2ARJ
2ARV
2ARW
2ARX
2ARZ
2AS0
|
|
gptkbp:protein_name
|
gptkb:Caspase-9
|
|
gptkbp:refersTo
|
gptkb:Caspase-9
|
|
gptkbp:RefSeq
|
NP_001220.2
|
|
gptkbp:sequence
|
416
|
|
gptkbp:status
|
Reviewed
|
|
gptkbp:subcellularLocation
|
gptkb:Mitochondrion
gptkb:Cytoplasm
|
|
gptkbp:tissue_specificity
|
Ubiquitous
|
|
gptkbp:UniGene
|
Hs.65462
|
|
gptkbp:bfsParent
|
gptkb:CASP9
gptkb:Caspase-9
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P55211
|