Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
CD49d
|
| gptkbp:associatedWith |
gptkb:Crohn's_disease
multiple sclerosis |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:ITGA4_gene
|
| gptkbp:expressedIn |
gptkb:leukocytes
monocytes lymphocytes |
| gptkbp:formsComplexWith |
gptkb:integrin_beta-1
gptkb:integrin_beta-7 |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
immune response
cell adhesion leukocyte migration |
| https://www.w3.org/2000/01/rdf-schema#label |
integrin alpha-4
|
| gptkbp:interactsWith |
gptkb:fibronectin
gptkb:MAdCAM-1 gptkb:VCAM-1 |
| gptkbp:locatedOnChromosome |
2q31-q32
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
150 kDa
|
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:target |
gptkb:natalizumab
|
| gptkbp:UniProtID |
P13612
|
| gptkbp:bfsParent |
gptkb:alpha-4_beta-1_integrin
gptkb:alpha-4_beta-7_integrin |
| gptkbp:bfsLayer |
7
|