Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Very Late Antigen-4
integrin alpha4beta1 |
| gptkbp:binds |
gptkb:fibronectin
gptkb:VCAM-1 |
| gptkbp:component |
integrin family
|
| gptkbp:composedOf |
alpha-4 subunit
beta-1 subunit |
| gptkbp:encodedBy |
gptkb:ITGA4_gene
ITGB1 gene |
| gptkbp:expressedIn |
gptkb:B_cells
gptkb:T_cells gptkb:eosinophils monocytes |
| gptkbp:foundIn |
gptkb:leukocytes
|
| gptkbp:function |
cell adhesion
lymphocyte migration |
| https://www.w3.org/2000/01/rdf-schema#label |
VLA-4
|
| gptkbp:involvedIn |
immune response
|
| gptkbp:involves |
multiple sclerosis
inflammatory diseases |
| gptkbp:role |
inflammation
leukocyte trafficking extravasation |
| gptkbp:structure |
heterodimer
|
| gptkbp:target |
gptkb:natalizumab
|
| gptkbp:bfsParent |
gptkb:alpha-4_beta-1_integrin
|
| gptkbp:bfsLayer |
7
|