|
gptkbp:instance_of
|
gptkb:Genetics
|
|
gptkbp:affects
|
mental health
quality of life
collagen production
|
|
gptkbp:can_cause
|
hearing loss
dental issues
|
|
gptkbp:can_detect
|
ultrasound in utero
|
|
gptkbp:can_lead_to
|
bone deformities
|
|
gptkbp:can_result_in
|
chronic pain
|
|
gptkbp:cause
|
brittle bones
|
|
gptkbp:complications
|
pregnancy
|
|
gptkbp:diagnosis
|
genetic testing
clinical evaluation
|
|
gptkbp:difficulty_levels
|
gptkb:Type_II
|
|
gptkbp:first_described_by
|
gptkb:Hippocrates
|
|
gptkbp:has_a_focus_on
|
clinical trials
|
|
gptkbp:has_achieved
|
scoliosis
|
|
gptkbp:has_type
|
gptkb:Type_I
gptkb:Type_II
gptkb:Type_III
Type IV
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
osteogenesis imperfecta
|
|
gptkbp:included
|
genetic counseling discussions
|
|
gptkbp:inherits_from
|
autosomal dominant inheritance
|
|
gptkbp:is_a_lifelong_condition
|
nan
|
|
gptkbp:is_a_subject_of
|
patient advocacy
|
|
gptkbp:is_affected_by
|
lack of physical activity
|
|
gptkbp:is_associated_with
|
cardiovascular issues
short stature
increased risk of fractures
blue sclera
|
|
gptkbp:is_characterized_by
|
variable severity
frequent fractures
|
|
gptkbp:is_linked_to_mutations_in
|
gptkb:COL1_A1_gene
gptkb:COL1_A2_gene
|
|
gptkbp:is_managed_by
|
bisphosphonates
orthopedic specialists
|
|
gptkbp:is_monitored_by
|
regular check-ups
|
|
gptkbp:is_often_seen_in
|
all ethnic groups
other bone disorders
|
|
gptkbp:is_recognized_by
|
medical professionals worldwide
|
|
gptkbp:is_studied_in
|
medical genetics
|
|
gptkbp:known_as
|
brittle bone disease
|
|
gptkbp:requires_multidisciplinary_care
|
nan
|
|
gptkbp:research
|
new therapies
|
|
gptkbp:scientific_classification
|
four main types
|
|
gptkbp:treatment
|
gptkb:surgery
medications
physical therapy
|
|
gptkbp:bfsParent
|
gptkb:Henri_de_Toulouse-Lautrec
|
|
gptkbp:bfsLayer
|
4
|