gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
gptkbp:alsoKnownAs
|
TIF1γ
Transcription intermediary factor 1-gamma
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:acute_myeloid_leukemia
|
gptkbp:discoveredBy
|
Rousseau et al.
|
gptkbp:discoveredIn
|
1995
|
gptkbp:domain
|
gptkb:bromodomain
RING finger domain
B-box domain
coiled-coil domain
PHD finger
|
gptkbp:encodedBy
|
TRIM33 gene
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000197323
51592
|
gptkbp:fullName
|
Tripartite motif-containing protein 33
|
gptkbp:function
|
transcriptional regulation
ubiquitin E3 ligase activity
|
gptkbp:geneType
|
protein-coding
|
gptkbp:HGNC_ID
|
HGNC:16290
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRIM33
|
gptkbp:interactsWith
|
gptkb:SMAD2
gptkb:SMAD3
gptkb:SMAD4
histone deacetylases
|
gptkbp:involvedIn
|
gptkb:TGF-beta_signaling_pathway
transcriptional repression
chromatin remodeling
|
gptkbp:length
|
1120 amino acids
|
gptkbp:locatedOnChromosome
|
1p13.2
|
gptkbp:molecularWeight
|
124 kDa
|
gptkbp:OMIM
|
607701
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
gptkbp:regulates
|
gptkb:SMAD2
gptkb:SMAD3
gptkb:SMAD4
|
gptkbp:species
|
gptkb:human
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
gptkbp:UniProtID
|
Q9UPN9
|
gptkbp:bfsParent
|
gptkb:anti-TIF1-gamma
|
gptkbp:bfsLayer
|
6
|