TRIM24

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alsoKnownAs TIF1α
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:cancer
liver cancer
prostate cancer
gptkbp:domain gptkb:bromodomain
RING finger domain
B-box domain
PHD finger
coiled-coil region
gptkbp:encodes TRIM24 protein
gptkbp:Entrez_Gene_ID 8805
ENSG00000197299
gptkbp:expressedIn gptkb:nucleus
various tissues
gptkbp:firstDescribed 1996
gptkbp:fullName Tripartite motif-containing protein 24
gptkbp:function E3 ubiquitin ligase
transcriptional co-regulator
gptkbp:gene gptkb:TRIM24
gptkbp:geneType protein-coding
gptkbp:hasParalog gptkb:TRIM33
gptkb:TRIM28
TRIM66
gptkbp:HGNC_ID HGNC:16819
https://www.w3.org/2000/01/rdf-schema#label TRIM24
gptkbp:interactsWith gptkb:p53
retinoic acid receptor alpha
gptkbp:involvedIn regulation of transcription
protein ubiquitination
gptkbp:length 1050
gptkbp:locatedOnChromosome gptkb:chromosome_7
gptkbp:memberOf gptkb:TRIM_protein_family
gptkbp:molecularWeight 116 kDa
gptkbp:mutationAssociatedWith tumorigenesis
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:regulates gene expression
chromatin structure
p53 stability
histone acetylation
transcriptional activity
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID O15164
gptkbp:bfsParent gptkb:7q34
gptkbp:bfsLayer 6