Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:component |
gptkb:DEPTOR
gptkb:PROTOR1 gptkb:PROTOR2 gptkb:RICTOR gptkb:mLST8 gptkb:mSIN1 gptkb:mTOR |
| gptkbp:discoveredIn |
2005
|
| gptkbp:fullName |
Target of Rapamycin Complex 2
|
| gptkbp:function |
regulation of cell survival
regulation of cytoskeleton regulation of metabolism phosphorylation of AKT |
| gptkbp:GO_term |
GO:0038202
|
| https://www.w3.org/2000/01/rdf-schema#label |
TORC2
|
| gptkbp:inhibitedBy |
rapamycin (in some contexts)
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:organism |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae gptkb:Homo_sapiens |
| gptkbp:pathway |
gptkb:PI3K/AKT_pathway
insulin signaling pathway |
| gptkbp:regulates |
gptkb:AKT1
gptkb:PKCĪ± gptkb:SGK1 |
| gptkbp:relatedTo |
TORC1
|
| gptkbp:UniProtID |
Q9BPZ7 (mSIN1)
Q9BVC4 (RICTOR) Q9BVC4 (mTOR) |
| gptkbp:bfsParent |
gptkb:AMPK_pathway
|
| gptkbp:bfsLayer |
6
|